![]() Trazodone should not be taken by pregnant women or women who are breastfeeding. It's not considered to be an addictive substance when used as prescribed.It's an inexpensive generic drug covered by most insurance companies.Because trazodone is not a controlled substance, physicians aren’t limited in how many pills they can prescribe.Both Ambien and Lunesta are classified by the FDA as controlled substances because they have the potential for misuse and abuse, including dependence or addiction.Trazodone differs from Ambien, Sonata, Lunesta and other "sleeping pill" medications in a few ways: How is trazodone different from other "sleeping pill" drugs? Common SSRIs are Prozac, Zoloft, Paxil, Lexapro, Celexa and Luvox common SNRIs include Cymbalta and Effexor and NDRIs are found in only one drug: Wellbutrin.īecause trazodone doesn’t fall under any of these categories, it’s often referred to as an "atypical antidepressant." Is it safe to take trazodone for insomnia?Īlthough trazodone was designed to treat depression and anxiety disorders, the medication is now widely prescribed as a nighttime sleep aid for patients who suffer from acute insomnia. There are three different types: selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and norepinephrine and dopamine reuptake inhibitors (NDRIs). Reuptake, as described by WebMD, is "the process in which neurotransmitters are naturally reabsorbed back into nerve cells in the brain after they are released to send messages between nerve cells." A reuptake inhibitor, then, keeps levels of neurotransmitters in the gap between nerves, potentially strengthening circuits in the brain that regulate mood. The most commonly prescribed antidepressants are reuptake inhibitors. While all antidepressant medications are designed to affect brain chemistry, various pharmaceutical formulations of the drugs have different targets and paths. Do all antidepressant drugs work the same way? Ask your physician to discuss all potential side effects as well as drug interactions and potential withdrawal symptoms associated with the medication. Like all medications, trazodone can cause side effects in some people. Is it safe to take trazodone to treat depression? Patients who take the drug as an antidepressant may not notice symptom relief for one to two weeks, and it may take up to four weeks to experience the full benefits. Patients who take the drug for a sleep disorder can experience the sedative effects within 30 minutes, depending on the type used. One of these important neurotransmitters-serotonin-regulates our internal clock for resting and being awake, as well as mood, appetite, digestion, memory, sexual function and desire. Many experts believe depression involves an imbalance among the brain’s neurotransmitters (acetylcholine, norepinephrine, dopamine and serotonin.) While the cause of depression is not fully understood, trazodone affects the brain's neurotransmitters by inhibiting the uptake of serotonin by nerves and stimulating other nerves. Trazodone increases natural neurotransmitters in the central nervous system, essentially restoring depleted chemicals in the brain. How does trazodone help to alleviate depression? Still, some people report lingering effects, including sluggishness and feeling zapped of energy, particularly upon waking. In prescribing the drug for sleep disorders, physicians typically recommend taking a low dose at bedtime in order to limit the effects of drowsiness. Does trazodone cause sleepiness?įor many patients, the drug has a sedative effect, inducing a relaxed, sleepy feeling. Today, the medication is prescribed under the brand name Oleptro to treat sleep disorders such as insomnia as well as anxiety disorder and unipolar depression. Food and Drug Administration (FDA) under the brand name Desyrel for use in treating major depressive disorder. In 1981, trazodone (the generic name of the pharmaceutical) was approved by the U.S. Eventually, however, internists and clinicians recognized potential benefits of the drug, particularly when administered at low doses. Due to negative side effects associated with the drug early on-including dizziness, fainting, irregular heartbeat (and in rare cases, priapism in men)-the antidepressant wasn’t widely favored in the medical community. Trazodone was developed in Italy in the 1960s as an antidepressant medication.
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